Projects and Collaborations

Projects

The BioPI department conducts projects exploring the interactions between inhaled particles and human health, in collaboration with renowned academic and industrial partners. This work covers various themes, ranging from toxicology to public health and the environment.

Nicotine salts and vaping

Toxicological challenges and pharmacological impact on nicotine delivery

  • Results
    Identification of health risks associated with the use of these salts and recommendations for stricter regulation.
  • Description
    This project explores the toxicological and pharmacological effects of nicotine salts used in e-liquids for vaping. The objective is to understand their impact on nicotine delivery and the potential risks associated with their inhalation.
  • Partner
    French National Cancer Institute (INCa)
    The French national agency dedicated to coordinating the fight against cancer, bringing together research, prevention, and therapeutic innovation.

Combined effects of tire wear particles and automobile exhaust gases on human health

  • Results
    Proposals to develop more sustainable materials and reduce harmful effects.
  • Description
    A thesis explores the health impact of particles generated by tire wear and exhaust gases, characterizing their physicochemical and toxicological properties.
  • Partner
    ADEME (French Agency for Ecological Transition)
    French agency committed to the energy and ecological transition, supporting research and innovation for sustainable development.

Improvement of ex-vivo lung perfusion through negative pressure ventilation and graft mobilization

ANR RÉVOLUTION

  • Results
    Optimisation of treatments for severe respiratory conditions requiring lung transplants.
  • Description
    Development of new ex vivo lung perfusion techniques, based on negative-pressure ventilation, to improve graft quality and effectiveness.
  • Partner
    ANR (French National Research Agency)

E-cigarettes and cardiovascular disease

in vitro study of biological damage induced by e-liquid condensates on aortic smooth muscle cells

  • Results
    In-depth understanding of the impacts of electronic cigarettes on the cardiovascular system and recommendations for their use.
  • Description
    This project analyzes the effects of e-liquid condensates on aortic smooth muscle cells to evaluate the induced biological damage and its potential links to cardiovascular diseases.

Emissions during waste treatment and regeneration processes and physicochemical and toxicological characterization of microplastics on an integrated site

  • Results
    Strategies to limit emissions and prevent risks to human health and the environment.
  • Description
    Study of particle and microplastic emissions during waste treatment and regeneration processes. Analysis of their physicochemical and toxicological properties directly on-site.
  • Partner
    ADEME (French Agency for Ecological Transition)
    French agency committed to the energy and ecological transition, supporting research and innovation for sustainable development.

These projects illustrate the BioPI department’s commitment to addressing health and environmental challenges related to inhaled particles, in collaboration with leading academic and industrial partners. They reinforce its role in developing innovative and sustainable solutions for public health.

Academic Partnerships

Industrial Partnerships

These partnerships reinforce the BioPI department’s role in developing innovative solutions and in understanding the impacts of inhaled particles on human health and industrial safety.

Research