Jérémie POURCHEZ

Jérémie POURCHEZ

Associate Professor
Entity
Centre for Biomedical and Healthcare Engineering
Department - Department
CIS – Direction – Secretariat – Services
Biological Activity of Inhaled NanoParticles (BioPI)
Site
CSI, Saint-Priest-en-Jarez
Email
pourchez@mines-stetienne.fr
Phone number
+33 4 77 42 01 80
Office
L307
    Biography

    Responsibilities and duties

    Jérémie POURCHEZ
    Full Professor in Aerosol Science and Toxicology
    Deputy Director of the Center for Biomedical and Healthcare Engineering (25 staff, 40 postgraduate students)
    Head of the “Biomaterials and Inhaled Particles” department (7 staff, 15 postgraduate students)

    Welcome to my professional web site: http://www.emse.fr/~pourchez/

    Skills

    Research Topics: Nanoparticle, Nanotoxicology, Aerosol Therapy, Particle Inhalation, Electronic cigarette

    Biography

    Jérémie Pourchez is Full-Professor at Mines Saint-Etienne. He is currently Deputy Director of the Center for Biomedical and Healthcare Engineering. Within this center, he is Head of the Biomaterials and Inhaled Particles Department. Professor Pourchez became, barely 12 years after his PhD defense in chemical engineering, a world- renowned expert on (nano)particles inhalation. Especially he developed an original interdisciplinary expertise applied to two borders fields: inhalation toxicology and respiratory drug delivery. His research interest and teaching include the understanding of inhaled nanoparticles fate within the organism to highlight biotoxicity, biodistribution and biopersistance of (nano)particles in living systems. His field of expertise is anatomic and cell targets of aerosol, physico-chemistry of nanoparticles and in vitro analysis of biological effects. The excellence of the research carried out results in the publication of more than 75 research papers (see http://www.emse.fr/~pourchez/biblio.html). The structuring of this scientific activity led to the emergence of his multidisciplinary group bringing together a community of researchers made of biologists, clinicians and engineers (UMR INSERM 1059 SAINBIOSE). This team permits to address in innovative fashion research questions on particle inhalation, from fundamental approaches to clinical applications, including pre-clinic studies and technological developments.

    Research topics

    Research topics

    ORGANISATION OF SCIENTIFIC MEETINGS
    2016 Member of the scientific board of the first “International Symposium dedicated to Electronic Nicotine Delivery Systems & Smoking Cessation”, 100 delegates, La Rochelle, France https://www.ecig-symposium.com/
    2016 Coordinator and session organizer, symposium on nanomaterials “Journées Industrielles Nanomines”, 60 delegates, Paris, France
    2013 Chairman and session organizer “Nanomicrotechnology Days for Health”, 80 participants, Saint-Etienne, France
    2010 Session organizer “Matériaux 2010”, 1600 delegates (20 conferences and 100 delegates in my session), Nantes, France
    2007 Member of the organizing committee and session organizer “SFGP 2007” for French Society of Process Engineering, 500 delegates (50 in my session), Saint-Etienne, France

    INSTITUTIONAL RESPONSIBILITIES
    Since 2015 In charge of the medical device axis of the transversal program Health Autonomy and Quality of Life of the Institut Mines Télécom (public institution dedicated to higher education, research and innovation in engineering and digital technologies)
    Since 2014 Vice-President of the I-care cluster on medical technologies (more than 100 companies)
    Member of the executive committee and the board of directors,the i-Care Cluster is an initiative intended to bring together all the stakeholders in the value chain of health technologies in the Auvergne – Rhône-Alpes Region – http://i-carecluster.org
    Since 2015 Member of the laboratory board, INSERM U1059, Saint-Etienne, France
    Since 2013 Deputy Director of the Center for Biomedical and Healthcare Engineering (CBHE)
    (25 staff, 40 postgraduate students), Mines Saint-Etienne / ARMINES, France
    Since 2012 Head of the “biomaterials and inhaled particles” department within CBHE
    (7 staff, 15 postgraduate students), Mines Saint-Etienne, France
    2011-2015 Co-founder and elected member of the board of directors of LINA, Interdisciplinary Laboratory for Aerosolized Nanoparticles, EA 4624, joint research group between medical doctors and engineers
    2010-2013 Member of the executive board and treasurer of IFRESIS INSERM SFR 143 and then FED 4166 (360 staff), Saint-Etienne, France
    2007-2010 Member of the laboratory board, CNRS 5148, Saint-Etienne, France

    Teaching areas

    Teaching areas

    TEACHING ACTIVITIES
    Since 2014 In charge of all the courses in biomedical engineering (320 hours of courses, 1 international MSc Program), Mines Saint-Etienne, France
    2007-2016 Teaching position (200 hours of courses per year) in biomaterials, aerosol science and toxicology for students from Mines Saint-Etienne, Jean Monnet University and one international MSc program in biomedical engineering

    Our academic standing is committed to excellence. Professor Pourchez coordinates the teaching activities dedicated to Biomedical and Healthcare Engineering at Mines Saint-Etienne. Furthermore, he specifically manages two dual degrees: the PharmD / ICM program and the MD / ICM program. Regularly ranked among the top 10 of the 230 French engineering courses, the ICM degree corresponds to a master degree in science and engineering combining broad theoretical knowledge with hands-on projects, development of management and communication skills. Theses combined Health-Engineering programs are designed for the highly motivated and qualified individuals who are seeking an integrated program in the clinical and engineering sciences preparing them for a career in academics research or industrial area.

    Education

    Education

    2012 Habilitation à Diriger des Recherches (HDR), Université Jean Monnet, France
    2003-2006 Ph.D. in Chemical Engineering, Mines Saint-Etienne, France
    2002-2003 Master of Science in Mathematics and Physics, Mines Saint-Etienne, France
    1999-2002 Master in Advanced Materials Science and Engineering, ESIREM, France
    1996-1999 Bachelor in Mathematics, Physics and Chemistry, French “classes préparatoires”, France

    Publications

    Main publications

    PUBLICATION LIST
    see https://www.emse.fr/~pourchez/biblio2.html

    COMMISSIONS OF TRUST
    Since 2010 Member of the commission “powder and sintered material” of the French Ceramic Group
    Since 2010 Reviewer of national science councils: ANR (France), ANSES (France), Discovery Grant (Canada)
    Since 2007 >20 PhD examination and committee member
    Since 2007 Reviewer for more than 10 international peer-review journals

    HAL Open Access Publications

    176 documents

    Journal articles145 document

    • Mariam Bitar, Jérémie Pourchez, Mohamad Sleiman, Laurent Bertoletti, Valérie Forest. Aromatic aldehydes formed during heating of cinnamon-flavored e-liquids drive pro-inflammatory responses in human aortic smooth muscle cells. Current Research in Toxicology, 2026, 10, pp.100299. ⟨10.1016/j.crtox.2026.100299⟩. ⟨hal-05624785⟩
    • Abderrahmane Bouredji, Bogdan Muresan-Paslaru, Riadh Lakhmi, Raphaël Passas, Jérémie Pourchez, et al.. Tire particles of different sizes induce a proinflammatory response of varying intensity in lung cells. Journal of Environmental Sciences, 2025, 158, pp.586-597. ⟨10.1016/j.jes.2025.03.011⟩. ⟨emse-05093928⟩
    • Codjo Camille Dedjiho, Agnès Crépet, Fifa Théomaine Diane Bothon, Cokou Pascal Agbangnan Dossa, Jean-Charles Majesté, et al.. New coacervates and crosslinkers from Araucaria heterophylla and Commiphora pedunculata exudates for microencapsulation of essential oils. Carbohydrate Polymer Technologies and Applications, 2025, 12, pp.101024. ⟨10.1016/j.carpta.2025.101024⟩. ⟨hal-05313926⟩
    • Abderrahmane Bouredji, Laurence Lumière, Riadh Lakhmi, Bogdan Muresan-Paslaru, Jérémie Pourchez, et al.. A toxicological comparison of tire and road wear particles emitted on rural and urban roads, alone or with the co-exposed pollutant benzo[a]pyrene: Size and origin as key factors in controlling the in vitro proinflammatory response. Environment International, 2025, 205, pp.109920. ⟨10.1016/j.envint.2025.109920⟩. ⟨hal-05359304⟩
    • Mariam Bitar, Jérémie Pourchez, Claire Le Hello, Laurent Bertoletti, Valérie Forest. E-cigarette and endothelial function -a critical review of preclinical studies. Chemical Research in Toxicology, 2025, ⟨10.1021/acs.chemrestox.5c00357⟩. ⟨hal-05349537⟩
    • Jérémie Pourchez, Clément Mercier, Valérie Forest. The rise of nicotine analogues in vaping products. The Lancet Respiratory Medicine, 2025, ⟨10.1016/S2213-2600(25)00296-6⟩. ⟨hal-05282493⟩
    • Ghalia Kaouane, Jean-François Berret, Yannick Crémillieux, Noël Pinaud, Fanny Munsch, et al.. Characterization of atomization and delivery efficiency of exogenous surfactant in preterm infant lungs using an ex vivo respiratory model. Scientific Reports, In press. ⟨hal-04750298v2⟩
    • Oumaima Marfouk, Ghalia Kaouane, Lara Leclerc, Fanny Munsch, Bei Zhang, et al.. MR Imaging of Pulmonary Surfactant Distribution in a Preclinical Neonatal Lung Model. NMR in Biomedicine, 2025, 38 (6), pp.e70053. ⟨10.1002/nbm.70053⟩. ⟨hal-05361563⟩
    • Rosy Ghanem, Raphaëlle Youf, Tanguy Haute, Xavier Buin, Martijn Riool, et al.. The (re)emergence of aerosol delivery: Treatment of pulmonary diseases and its clinical challenges. Journal of Controlled Release, 2025, 379, pp.421-439. ⟨10.1016/j.jconrel.2025.01.017⟩. ⟨hal-04966479⟩
    • Rosy Ghanem, Xavier Buin, Tanguy Haute, Justine Philippe, Ghalia Kaouane, et al.. Impact of nebulizers on nanoparticles-based gene delivery efficiency: in vitro and in vivo comparison of jet and mesh nebulizers using branched-polyethyleneimine. Drug Delivery, 2025, 32 (1), ⟨10.1080/10717544.2025.2463428⟩. ⟨hal-04966482⟩
    • Valérie Forest, Jérémie Pourchez, Emmanuel Flahaut. Efficiency and safety of nanopesticides, it takes two to tango. An overview of the lack of data on possible effects on human health. Science of the Total Environment, 2025, 973, pp.179156. ⟨10.1016/J.SCITOTENV.2025.179156⟩. ⟨hal-05000137⟩
    • Emma Eynaud, Lara Leclerc, Manon Moreau-Neidhardt, Jérémie Pourchez. Comparative performance study of paperboard disposable spacers versus commercial valved holding chambers for aerosol delivery. International Journal of Pharmaceutics, 2024, 666, pp.124774. ⟨10.1016/j.ijpharm.2024.124774⟩. ⟨hal-04807084⟩
    • Alice Kheng, Lara Leclerc, Martin Fayolle, Florence Grattard, Paul Verhoeven, et al.. Evaluation of the penetration capacity of bacteria through layers of different face mask types and wearing conditions. Scientific Reports, 2024, 14 (1), pp.25906. ⟨10.1038/s41598-024-76744-9⟩. ⟨hal-04966491⟩
    • Jérémie Pourchez, Clément Mercier, Lara Leclerc, Valérie Forest. The recent explosion in snortable energy powder consumption. The Lancet Respiratory Medicine, 2024, 12 (8), pp.e47. ⟨10.1016/S2213-2600(24)00188-7⟩. ⟨hal-04966484⟩
    • Clément Mercier, Jérémie Pourchez, Lara Leclerc, Valérie Forest. In vitro toxicological evaluation of aerosols generated by a 4th generation vaping device using nicotine salts in an air-liquid interface system. Respiratory Research, 2024, 25 (1), pp.75. ⟨10.1186/s12931-024-02697-2⟩. ⟨hal-04807074⟩
    • Cyrille Bruneau, Clément Mercier, Lara Leclerc, Jérémie Pourchez. The Ability of Vaping Technology to Deliver an Equivalent Respirable Dose of Beclomethasone Dipropionate Compared to Nebulization. Pharmaceutics, 2024, 16 (11), pp.1396. ⟨10.3390/pharmaceutics16111396⟩. ⟨hal-04807091⟩
    • Mariam Chaoui, Emmanuelle Fischer, Sophie Perinel-Ragey, Nathalie Prévôt, Lara Leclerc, et al.. Development of a Novel Bronchodilator Vaping Drug Delivery System Based on Thermal Degradation Properties. Pharmaceuticals, 2023, 16 (12), pp.1730. ⟨10.3390/ph16121730⟩. ⟨hal-04887728⟩
    • Kévin Bernal, Ozge Kose, Lara Leclerc, Jean-Michel Vergnon, Jérémie Pourchez, et al.. Development of a protocol of isolation of nanoparticles from patients' broncho-alveolar lavages for their in vitro toxicity assessment. Nanoscale Advances, 2023, ⟨10.1039/d3na00918a⟩. ⟨hal-04328394⟩
    • Valérie Forest, Jérémie Pourchez. Biological effects of brake wear particles in mammalian models: a systematic review. Science of the Total Environment, 2023, 905, pp.167266. ⟨10.1016/j.scitotenv.2023.167266⟩. ⟨hal-04228704⟩
    • C. Rousseau, Jérémie Pourchez, L. Leclerc, M. Nekaa, T. Raia-Barjat. Usage du tabac et de la cigarette électronique chez la femme enceinte : une étude transversale. Gynécologie Obstétrique Fertilité & Sénologie, 2023, 51 (10), pp.455-462. ⟨10.1016/j.gofs.2023.07.004⟩. ⟨hal-04887724⟩
    • Oveis Pourmehran, Kavan Zarei, Jérémie Pourchez, Sarah Vreugde, Alkis Psaltis, et al.. Advancements in acoustic drug delivery for paranasal sinuses: A comprehensive review. International Journal of Pharmaceutics, 2023, 644, pp.123277. ⟨10.1016/j.ijpharm.2023.123277⟩. ⟨hal-04887721⟩
    • Valérie Forest, Jérémie Pourchez. Can the impact of micro-and nanoplastics on human health really be assessed using in vitro models? A review of methodological issues. Environment International, 2023, 178, pp.108115. ⟨10.1016/j.envint.2023.108115⟩. ⟨hal-04183940⟩
    • Yoann Montigaud, Quentin Georges, Lara Leclerc, Anthony Clotagatide, Aurore Louf-Durier, et al.. Impact of gas humidification and nebulizer position under invasive ventilation: preclinical comparative study of regional aerosol deposition. Scientific Reports, 2023, 13 (1), pp.11056. ⟨10.1038/s41598-023-38281-9⟩. ⟨hal-04887730⟩
    • Louise Wittmann, Joseph Garnier, Naomi Sakata, Elisabeth Auzias, Martin Dumoulin, et al.. Structure, Morphology, and Surface Chemistry of Surgical Masks and Their Evolution up to 10 Washing Cycles. ACS Applied Polymer Materials, 2023, 5 (3), pp.2282-2288. ⟨10.1021/acsapm.3c00145⟩. ⟨hal-04106860⟩
    • Manon Moreau-Neidhardt, Lara Leclerc, Jeanne Grange, Sophie Périnel, Jérémie Pourchez. Assessing of low-tech solutions for aerosol delivery: Comparative performance study of manufactured versus homemade spacers. International Journal of Pharmaceutics, 2023, 633, pp.122652. ⟨10.1016/j.ijpharm.2023.122652⟩. ⟨hal-04966464⟩
    • Lara Leclerc, Nathalie Prévôt, Sophie Hodin, Xavier Delavenne, Heribert Mentzel, et al.. Acoustic Aerosol Delivery: Assessing of Various Nasal Delivery Techniques and Medical Devices on Intrasinus Drug Deposition. Pharmaceuticals, 2023, 16 (2), pp.135. ⟨10.3390/ph16020135⟩. ⟨hal-05026204⟩
    • Maxime Beal, Mohamed-Nour Azzougagh, Jérémie Pourchez, Philippe Bertrand, Elodie Cabrol, et al.. Effect of powder reuse on physical, chemical and toxicological properties of 6061-Zr aluminum alloy processed by Laser Powder Bed Fusion (L-PBF). Matériaux et Techniques, 2023, 111 (1), pp.103. ⟨10.1051/mattech/2023013⟩. ⟨hal-04109263⟩
    • Axel Fouqueau, Jérémie Pourchez, Lara Leclerc, Aurélien Peyron, Yoann Montigaud, et al.. Inter-laboratory Comparison between Particle and Bacterial Filtration Efficiencies of Medical Face Masks in the COVID-19 Context. Aerosol and Air Quality Research, 2023, 23 (2), pp.220252. ⟨10.4209/aaqr.220252⟩. ⟨hal-04966459⟩
    • Abderrahmane Bouredji, Jérémie Pourchez, Valérie Forest. Biological effects of Tire and Road Wear Particles (TRWP) assessed by in vitro and in vivo studies - a systematic review. Science of the Total Environment, 2023, 894, pp.164989. ⟨10.1016/j.scitotenv.2023.164989⟩. ⟨hal-04145530⟩
    • Sana Djeghdir, Aurélien Peyron, Gwendoline Sarry, Lara Leclerc, Ghalia Kaouane, et al.. Filtration efficiency of medical and community face masks using viral and bacterial bioaerosols. Scientific Reports, 2023, 13 (1), pp.7115. ⟨10.1038/s41598-023-34283-9⟩. ⟨hal-04807119⟩
    • Valérie Forest, Clément Mercier, Jérémie Pourchez. Considerations on dosimetry for in vitro assessment of e-cigarette toxicity. Respiratory Research, 2022, 23 (1), pp.358. ⟨10.1186/s12931-022-02286-1⟩. ⟨hal-03921767⟩
    • Caroline Marie-Desvergne, Muriel Dubosson, Lara Leclerc, Catherine Campo, Dimitrios Bitounis, et al.. Characterization of the elemental and particle load of patient exhaled breath condensate and comparison with pulmonary lavages. Journal of Breath Research, 2022, 17 (1), pp.016008. ⟨10.1088/1752-7163/aca697⟩. ⟨hal-04966456⟩
    • Marine Michon, Clément Mercier, Claudie Petit, Lara Leclerc, Laurent Bertoletti, et al.. In Vitro Biological Effects of E-Cigarette on the Cardiovascular System—Pro-Inflammatory Response Enhanced by the Presence of the Cinnamon Flavor. Toxics, 2022, 10 (12), pp.784. ⟨10.3390/toxics10120784⟩. ⟨hal-03921778⟩
    • Henrietta Essie Whyte, Aurélie Joubert, Lara Leclerc, Gwendoline Sarry, Paul Verhoeven, et al.. Reusability of face masks: Influence of washing and comparison of performance between medical face masks and community face masks. Environmental Technology and Innovation, 2022, 28, pp.102710. ⟨10.1016/j.eti.2022.102710⟩. ⟨hal-03844335v2⟩
    • Mariam Chaoui, Sophie Perinel-Ragey, Nathalie Prévôt, Lara Leclerc, Jérémie Pourchez. Technical features of vaping drug delivery system for bronchodilator delivery. International Journal of Pharmaceutics, 2022, 628 (12), pp.122350. ⟨10.1016/j.ijpharm.2022.122350⟩. ⟨hal-04966495⟩
    • Jérémie Pourchez, Aurélien Peyron, Gwendoline Sarry, Lara Leclerc, Paul O Verhoeven, et al.. Antimicrobial Performance of an Innovative Technology of Atmospheric Plasma Reactors against Bioaerosols: Effectiveness in Removing Airborne Viable Viruses. Buildings, 2022, 12 (10), pp.1587. ⟨10.3390/buildings12101587⟩. ⟨hal-03844383⟩
    • V. Forest, J. Pourchez. Human biological monitoring of nanoparticles, a new way to investigate potential causal links between exposure to nanoparticles and lung diseases?. Pediatric Pulmonology, 2022, 29 (1), pp.4 - 5. ⟨10.1016/j.pulmoe.2022.08.005⟩. ⟨hal-03921786⟩
    • V. Forest, J. Pourchez. Human biological monitoring of nanoparticles, a new way to investigate potential causal links between exposure to nanoparticles and lung diseases?. Pediatric Pulmonology, 2022, ⟨10.1016/j.pulmoe.2022.08.005⟩. ⟨hal-03844345⟩
    • Jérémie Pourchez, Clément Mercier, Valérie Forest. From smoking to vaping: a new environmental threat?. The Lancet Respiratory Medicine, 2022, 10 (7), pp.e63-e64. ⟨10.1016/S2213-2600(22)00187-4⟩. ⟨hal-04966496⟩
    • Valérie Forest, Jérémie Pourchez. Nano-delivery to the lung - by inhalation or other routes and why nano when micro is largely sufficient?. Advanced Drug Delivery Reviews, 2022, 183, pp.114173. ⟨10.1016/j.addr.2022.114173⟩. ⟨hal-03610343⟩
    • Mariam Chaoui, Sophie Chevrel, Sophie Perinel-Ragey, Nathalie Prévôt, Jérémie Pourchez. Assessment of High-Power Electronic Nicotine Delivery System as an Alternative Aerosol Device for Terbutaline Delivery. Pharmaceutical Research, 2022, 39 (3), pp.587-597. ⟨10.1007/s11095-022-03187-0⟩. ⟨hal-03844353⟩
    • Hélène Niculita-Hirzel, Audrey S Vanhove, Lara Leclerc, Françoise Girardot, Jérémie Pourchez, et al.. Risk Exposure to Legionella pneumophila during Showering: The Difference between a Classical and a Water Saving Shower System. International Journal of Environmental Research and Public Health, 2022, 19 (6), pp.3285. ⟨10.3390/ijerph19063285⟩. ⟨hal-03844363⟩
    • Mohamed-Nour Azzougagh, François-Xavier Keller, Mehmet Cici, Elodie Cabrol, Jérémie Pourchez. Ultrafine aerosol transient phase measurement with real-time monitoring instrument applied to cleaning process of L-Pbf machine. Toxicology and Environmental Health Sciences, 2022, 14 (1), pp.59-68. ⟨10.1007/s13530-021-00117-2⟩. ⟨hal-03844360⟩
    • Quentin Armand, Henrietta Essie Whyte, Paul Verhoeven, Florence Grattard, Lara Leclerc, et al.. Impact of medical face mask wear on bacterial filtration efficiency and breathability. Environmental Technology and Innovation, 2022, 28, pp.102897. ⟨10.1016/j.eti.2022.102897⟩. ⟨hal-03844390⟩
    • Henrietta Essie Whyte, Yoann Montigaud, Estelle Audoux, Paul Verhoeven, Amélie Prier, et al.. Comparison of bacterial filtration efficiency vs. particle filtration efficiency to assess the performance of non-medical face masks. Scientific Reports, 2022, 12 (1), pp.1188. ⟨10.1038/s41598-022-05245-4⟩. ⟨hal-03844342⟩
    • C. Chivas-Joly, Claire Longuet, L. Leclerc, G. Sarry, V. Forest, et al.. Physicochemical characterization and toxicity of nanowaste after incineration process of PA-6/PP/ZnO or TiO 2 nanocomposites. Environmental science‎.Nano, 2022, 9 (12), pp.4570-4584. ⟨10.1039/D2EN00630H⟩. ⟨hal-03866038⟩
    • J. Pourchez. Chapter in “Biosafety and biosecurity approaches to counter SARS-COV-2 from detection to best practices and risk assessments”. Frontiers research topics, In press. ⟨hal-03844758⟩
    • Mohamed-Nour Azzougagh, Francois-Xavier Keller, Mehmet Cici, Elodie Cabrol, Jeremie Pourchez. Ultrafine aerosol transient phase measurement with real-time monitoring instrument applied to cleaning process of L-Pbf machine. Toxicology and Environmental Health Sciences, 2022, 14 (1), pp.59-68. ⟨10.1007/s13530-021-00117-2⟩. ⟨hal-04083024⟩
    • Salma Achawi, Ludovic Huot, Fabrice Nesslany, Jérémie Pourchez, Sophie Simar, et al.. Exploring graphene-based materials’ genotoxicity: inputs of a screening method. Nanotoxicology, 2021, 15 (10), pp.1279-1294. ⟨10.1080/17435390.2021.2018734⟩. ⟨hal-03610337⟩
    • Salma Achawi, Bruno Feneon, Jérémie Pourchez, Valérie Forest. Structure–Activity Relationship of Graphene-Based Materials: Impact of the Surface Chemistry, Surface Specific Area and Lateral Size on Their In Vitro Toxicity. Nanomaterials, 2021, 11 (11), pp.2963. ⟨10.3390/nano11112963⟩. ⟨hal-03423385⟩
    • Valérie Forest, Jérémie Pourchez, Carole Pélissier, Sabyne Audignon Durand, Jean-Michel Vergnon, et al.. Relationship between occupational exposure to airborne nanoparticles, nanoparticle lung burden and lung diseases. Toxics, 2021, 9 (9), pp.204. ⟨10.3390/toxics9090204⟩. ⟨hal-03330892⟩
    • Mohamed Nour Azzougagh, Francois-Xavier Keller, Elodie Cabrol, Mehmet Cici, Jérémie Pourchez. Occupational exposure during metal additive manufacturing: A case study of laser powder bed fusion of aluminum alloy. Journal of Occupational and Environmental Hygiene, 2021, 18 (6), pp.223-236. ⟨10.1080/15459624.2021.1909055⟩. ⟨hal-04966501⟩
    • Ozge Kose, Maura Tomatis, Francesco Turci, Naila-Besma Belblidia, Jean-François Hochepied, et al.. Short pre-irradiation of TiO2 nanoparticles increases cytotoxicity on human lung coculture system. Chemical Research in Toxicology, 2021, 34 (3), pp.733-742. ⟨10.1021/acs.chemrestox.0c00354⟩. ⟨hal-03330836⟩
    • Jérémie Pourchez, Aurélien Peyron, Yoann Montigaud, Coralie Laurent, Estelle Audoux, et al.. New insights into the standard method of assessing bacterial filtration efficiency of medical face masks. Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-85327-x⟩. ⟨hal-04807117⟩
    • Yoann Montigaud, Baptiste Manzotti, Sophie Chevrel, Lara Leclerc, Gwendoline Sarry, et al.. Aerosol regional deposition of electronic cigarette emissions using an original ex vivo respiratory model. Journal of Aerosol Science, 2021, 151, pp.105633 -. ⟨10.1016/j.jaerosci.2020.105633⟩. ⟨hal-03491965⟩
    • Salma Achawi, Jérémie Pourchez, Bruno Feneon, Valérie Forest. Graphene-Based Materials In Vitro Toxicity and Their Structure–Activity Relationships: A Systematic Literature Review. Chemical Research in Toxicology, 2021, ⟨10.1021/acs.chemrestox.1c00243⟩. ⟨hal-03330815⟩
    • Salma Achawi, Bruno Feneon, Jérémie Pourchez, Valérie Forest. Assessing biological oxidative damage induced by graphene-based materials: An asset for grouping approaches using the FRAS assay. Regulatory Toxicology and Pharmacology, 2021, 127, pp.105067. ⟨10.1016/j.yrtph.2021.105067⟩. ⟨hal-03400791⟩
    • Hélène Lalo, Lara Leclerc, Jérémy Sorin, Jérémie Pourchez. Aerosol droplet-size distribution and airborne nicotine portioning in particle and gas phases emitted by electronic cigarettes. Scientific Reports, 2020, 10 (1), pp.21707. ⟨10.1038/s41598-020-78749-6⟩. ⟨hal-04966503⟩
    • Louis Bernard, Guillaume Desoubeaux, Elsa Bodier-Montagutelli, Jeoffrey Pardessus, Deborah Brea, et al.. Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission. Frontiers in Medicine, 2020, 7, 9 p. ⟨10.3389/fmed.2020.584036⟩. ⟨hal-03036466⟩
    • Yoann Montigaud, Jérémie Pourchez, Lara Leclerc, Olivier Tillement, Anthony Clotagatide, et al.. Nebulised Gadolinium-Based Nanoparticles for a Multimodal Approach: Quantitative and Qualitative Lung Distribution Using Magnetic Resonance and Scintigraphy Imaging in Isolated Ventilated Porcine Lungs. International Journal of Nanomedicine, 2020, Volume15, pp.7251 - 7262. ⟨10.2147/ijn.s260640⟩. ⟨hal-02993422⟩
    • Sandrine Le Guellec, Laurine Allimonnier, Nathalie Heuzé-Vourc'H, Maria Cabrera, Frédéric Ossant, et al.. Low-Frequency Intrapulmonary Percussive Ventilation Increases Aerosol Penetration in a 2-Compartment Physical Model of Fibrotic Lung Disease. Frontiers in Bioengineering and Biotechnology, 2020, 8, ⟨10.3389/fbioe.2020.01022⟩. ⟨hal-03687289⟩
    • Ozge Kose, Maura Tomatis, Lara Leclerc, Naila-Besma Belblidia, Jean-François Hochepied, et al.. Impact of the Physicochemical Features of TiO2 Nanoparticles on Their In Vitro Toxicity. Chemical Research in Toxicology, 2020, ⟨10.1021/acs.chemrestox.0c00106⟩. ⟨hal-02923542⟩
    • Yannick Cremillieux, Yoann Montigaud, Clémence Bal, Noël Pinaud, Vi Pham, et al.. Three‐dimensional quantitative MRI of aerosolized gadolinium‐based nanoparticles and contrast agents in isolated ventilated porcine lungs. Magnetic Resonance in Medicine, 2020, 83 (5), pp.1774-1782. ⟨10.1002/mrm.28041⟩. ⟨hal-02382227⟩
    • Claire Longuet, Carine Chivas-Joly, Lara Leclerc, Gwendoline Sarry, José-Marie Lopez-Cuesta, et al.. Caractérisation des transformations physico-chimiques de nanocomposites après incinération et conséquences biologiques des émissions. Environnement, Risques & Santé, 2020, 19 (Supplément 1), pp.51-64. ⟨10.1684/ers.2020.1413⟩. ⟨hal-02553191⟩
    • Odile Sabido, Agathe Figarol, Jean-Philippe Klein, Valérie Bin, Valérie Forest, et al.. Quantitative Flow Cytometric Evaluation of Oxidative Stress and Mitochondrial Impairment in RAW 264.7 Macrophages after Exposure to Pristine, Acid Functionalized, or Annealed Carbon Nanotubes. Nanomaterials, 2020, 10 (2), pp.319. ⟨10.3390/nano10020319⟩. ⟨hal-03740357⟩
    • Séverine Allegra, Serge Riffard, Lara Leclerc, Françoise Girardot, Magalie Stauffert, et al.. A valuable experimental setup to model exposure to Legionella’s aerosols generated by shower-like systems. Water Research, 2020, ⟨10.1016/j.watres.2020.115496⟩. ⟨hal-02468422⟩
    • Tiphaine Raia-Barjat, Carole Prieux, Lara Leclerc, Gwendoline Sarry, Lucile Grimal, et al.. Elemental fingerprint of human amniotic fluids and relationship with potential sources of maternal exposure. Journal of Trace Elements in Medicine and Biology, 2020, 60, pp.126477. ⟨10.1016/j.jtemb.2020.126477⟩. ⟨hal-02496639⟩
    • Yoann Montigaud, Quentin Georges, Jérémie Pourchez, Lara Leclerc, Clémence Goy, et al.. Aerosol delivery during invasive mechanical ventilation: development of a preclinical ex vivo respiratory model for aerosol regional deposition. Scientific Reports, 2019, 9 (1), pp.17930. ⟨10.1038/s41598-019-54480-9⟩. ⟨hal-04966512⟩
    • Clémence Goy, Jérémie Pourchez, Yoann Montigaud, Sophie Perinel-Ragey, Laurent Plantier, et al.. Development of an ex vivo preclinical respiratory model of idiopathic pulmonary fibrosis for aerosol regional studies. Scientific Reports, 2019, 9 (1), pp.17949. ⟨10.1038/s41598-019-54479-2⟩. ⟨hal-02554960⟩
    • C. Denis-Vatant, C. Merieux, L. Leclerc, H. Duc, C. Berton, et al.. Relations entre vapotage et tabagisme chez les adolescents en classe de seconde. Résultats d’une étude observationnelle descriptive transversale et monocentrique menée dans l’agglomération stéphanoise. Revue des Maladies Respiratoires, 2019, 36, pp.850 - 860. ⟨10.1016/j.rmr.2019.04.002⟩. ⟨hal-03487932⟩
    • Valérie Forest, Jean-François Hochepied, Jérémie Pourchez. Importance of Choosing Relevant Biological End Points To Predict Nanoparticle Toxicity with Computational Approaches for Human Health Risk Assessment. Chemical Research in Toxicology, 2019, 32 (7), pp.1320-1326. ⟨10.1021/acs.chemrestox.9b00022⟩. ⟨hal-02189302⟩
    • Laurent Navarro, Lara Leclerc, Jérémie Pourchez. Does Acoustic Overlay of Music Improve Aerosol Penetration into Maxillary Sinuses?. Online Journal of Otolaryngology and Rhinology, 2019. ⟨hal-02178026⟩
    • Valérie Forest, Jean-François Hochepied, Lara Leclerc, Adeline Trouvé, Khalil Abdelkebir, et al.. Towards an alternative to nano-QSAR for nanoparticle toxicity ranking in case of small datasets. Journal of Nanoparticle Research, 2019, 21 (5), ⟨10.1007/s11051-019-4541-2⟩. ⟨hal-02132406⟩
    • Magali Ferro, Lara Leclerc, Mohamad Sleiman, Bastien Marchiori, Jérémie Pourchez, et al.. Effect of E cigarettes on tracheal cells monitored at the air-liquid interface using an organic electrochemical transistor. Advanced Biosystems, 2019, 3 (3), pp.1800249. ⟨10.1002/adbi.201800249⟩. ⟨hal-02080289⟩
    • Yoann Montigaud, Sophie Perinel, Jean-Christophe Dubus, Lara Leclerc, Marie Suau, et al.. Development of an ex vivo respiratory pediatric model of bronchopulmonary dysplasia for aerosol deposition studies. Scientific Reports, 2019, 9 (1), pp.5720. ⟨10.1038/s41598-019-42103-2⟩. ⟨hal-02096000⟩
    • C. Chivas-Joly, C. Longuet, J. Pourchez, L. Leclerc, G. Sarry, et al.. Physical, morphological and chemical modification of Al-based nanofillers in by-products of incinerated nanocomposites and related biological outcome. Journal of Hazardous Materials, 2019, 365, pp.405-412. ⟨10.1016/j.jhazmat.2018.10.029⟩. ⟨hal-02080283⟩
    • Valérie Forest, Jérémie Pourchez, Cyril Guibert, Dimitrios Bitounis, Lara Leclerc, et al.. Nano to micron-sized particle detection in patients' lungs and its pathological significance. Environmental science‎.Nano, In press, ⟨10.1039/C8EN01301B⟩. ⟨hal-02093051⟩
    • Philippe Bertrand, Vincent Bonnarme, Antoine Piccirilli, Philippe Ayrault, Laurent Lemée, et al.. Physical and chemical assessment of 1,3 Propanediol as a potential substitute of propylene glycol in refill liquid for electronic cigarettes. Scientific Reports, 2018, 8 (1), pp.10702. ⟨10.1038/s41598-018-29066-6⟩. ⟨hal-01899506⟩
    • Shima Jowhari Moghadam, Laurent Navarro, Lara Leclerc, Sophie Hodin, Jérémie Pourchez. Toward smart Nebulization: Engineering acoustic airflow to penetrate maxillary sinuses in chronic rhinosinusitis. International Journal of Pharmaceutics, 2018, 546 (1-2), pp.188-193. ⟨10.1016/j.ijpharm.2018.05.039⟩. ⟨hal-02080208⟩
    • Jérémie Pourchez, Valérie Forest. E-cigarettes: from nicotine to cannabinoids, the French situation. The Lancet Respiratory Medicine, 2018, 6 (5). ⟨hal-01891306⟩
    • Jérémie Pourchez, Sandrine Parisse, Gwendoline Sarry, Sophie Perinel-Ragey, Jean-Michel Vergnon, et al.. Impact of power level and refill liquid composition on the aerosol output and particle size distribution generated by a new-generation e-cigarette device. Aerosol Science and Technology, 2018, 52 (4), pp.359 - 369. ⟨10.1080/02786826.2017.1422857⟩. ⟨hal-01899515⟩
    • Yoann Montigaud, Sophie Perinel, Jean-Christophe Dubus, Marie Suau, Lara Leclerc, et al.. Late Breaking Abstract - Development of an ex vivo pediatric preclinical model of bronchopulmonary dysplasia for aerosol regional deposition studies. European Respiratory Journal, 2018, 52 (62), ⟨10.1183/13993003.congress-2018.OA519⟩. ⟨hal-02143652⟩
    • Dimitrios Bitounis, Vincent Barnier, Cyril Guibert, Jérémie Pourchez, Valérie Forest, et al.. A method for the quantitative extraction of gold nanoparticles from human bronchoalveolar lavage fluids through a glycerol gradient. Nanoscale, 2018, 10 (6), pp.2955-2969. ⟨10.1039/C7NR04484D⟩. ⟨hal-01806118⟩
    • Dimitrios Bitounis, Jean-Philippe Klein, Lionel Maurice Edouard Mery, Amira El Merhie, Valérie Forest, et al.. Ex vivo detection and quantification of gold nanoparticles in human seminal and follicular fluids. Analyst, 2018, 143 (2), pp.475 - 486. ⟨10.1039/c7an01641g⟩. ⟨hal-01896549⟩
    • Sophie Perinel, Valérie Forest, Mathilde Landraud, Jérémie Pourchez, Françoise Girardot, et al.. Deposition pattern of aerosolized Legionella using an ex vivo human-porcine respiratory model. International Journal of Hygiene and Environmental Health, 2018, 221 (2), pp.252-259. ⟨10.1016/j.ijheh.2017.11.002⟩. ⟨hal-01690771⟩
    • Valérie Forest, Jean-Michel Vergnon, Cyril Guibert, Dimitrios Bitounis, Lara Leclerc, et al.. Metal load assessment in patient pulmonary lavages: towards a comprehensive mineralogical analysis including the nano-sized fraction. Nanotoxicology, In press. ⟨hal-01680403⟩
    • Jérémie Pourchez, Carine Chivas-Joly, Claire Longuet, Lara Leclerc, Gwendoline Sarry, et al.. End-of-life incineration of nanocomposites: new insights on nanofillers partitioning into by-products and biological outcomes of airborne emission and residual ash. Environmental science‎.Nano, 2018, 5, pp.1951-1964. ⟨10.1039/C8EN00420J⟩. ⟨hal-02080277⟩
    • Jérémie Pourchez, Lara Leclerc, Françoise Girardot, Serge Riffard, Nathalie Prevot, et al.. Experimental human-like model to assess the part of viable Legionella reaching the thoracic region after nebulization. PLoS ONE, 2017, 12 (10), pp.e0186042. ⟨10.1371/journal.pone.0186042⟩. ⟨hal-01680381⟩
    • Valérie Forest, Jean-Michel Vergnon, Jérémie Pourchez. Biological monitoring of inhaled nanoparticles in patients: an appealing approach to study causal link between human respiratory pathology and exposure to nanoparticles. Chemical Research in Toxicology, 2017. ⟨hal-01680460⟩
    • Valérie Forest, Lara Leclerc, Jean-François Hochepied, Adeline Trouvé, Gwendoline Sarry, et al.. Impact of cerium oxide nanoparticles shape on their in vitro cellular toxicity. Toxicology in Vitro, 2017, 38, pp.136-141. ⟨10.1016/j.tiv.2016.09.022⟩. ⟨hal-01421912⟩
    • Nathalie Prevot, Fabien de Oliveira, Sophie Perinel-Ragey, Thierry Basset, Jean-Michel Vergnon, et al.. Nicotine delivery from the refill liquid to the aerosol via high-power e-cigarette device. Scientific Reports, 2017, 7, pp.2592. ⟨10.1038/s41598-017-03008-0⟩. ⟨hal-01680481⟩
    • J. Pourchez, L. Leclerc, G. Sarry, J. -M. Vergnon, J. C. Dubus. Bench-test evaluation of spacer devices for fluticasone delivery to infants. Revue des Maladies Respiratoires, 2017, 34 (1), pp.29-35. ⟨10.1016/j.rmr.2016.02.009⟩. ⟨hal-01496181⟩
    • Valérie Forest, Jérémie Pourchez. Preferential binding of positive nanoparticles on cell membranes is due to electrostatic interactions: A too simplistic explanation that does not take into account the nanoparticle protein corona. Materials Science and Engineering: C, 2017, 70, pp.889 - 896. ⟨10.1016/j.msec.2016.09.016⟩. ⟨hal-01890942⟩
    • Jérémie Pourchez, Fabien de Oliveira, Sophie Perinel-Ragey, Thierry Basset, Jean-Michel Vergnon, et al.. Assessment of new-generation high-power electronic nicotine delivery system as thermal aerosol generation device for inhaled bronchodilators. International Journal of Pharmaceutics, 2017. ⟨hal-01889941⟩
    • Andréa Kurtz-Chalot, Christian L. Villiers, Jérémie Pourchez, Delphine Boudard, Matteo Martini, et al.. Impact of silica nanoparticle surface chemistry on protein corona formation and consequential interactions with biological cells. Materials Science and Engineering: C, 2017, ⟨10.1016/j.msec.2017.02.028⟩. ⟨hal-01680498⟩
    • Valérie Forest, Jérémie Pourchez. The nanoparticle protein corona: The myth of average. Nano Today, 2016, 11 (6), pp.700 - 703. ⟨10.1016/j.nantod.2015.10.007⟩. ⟨hal-01890993⟩
    • Nathalie Douard, Lara Leclerc, Gwendoline Sarry, Valérie Bin, David Marchat, et al.. Impact of the chemical composition of poly-substituted hydroxyapatite particles on the in vitro pro-inflammatory response of macrophages. Biomedical Microdevices, 2016, 18 (2), ⟨10.1007/s10544-016-0056-0⟩. ⟨hal-01321154⟩
    • Séverine Allegra, Lara Leclerc, Pierre André Massard, Françoise Girardot, Serge Riffard, et al.. Characterization of aerosols containing Legionella generated upon nebulization. Scientific Reports, 2016, 6 (1), ⟨10.1038/srep33998⟩. ⟨hal-02100265⟩
    • Amira El Merhie, Laurent Navarro, Xavier Delavenne, Lara Leclerc, Jérémie Pourchez. A new Strategy to Improve Drug Delivery to the Maxillary Sinuses: The Frequency Sweep Acoustic Airflow. Pharmaceutical Research, 2016, 33 (5), pp.1074-1084. ⟨10.1007/s11095-015-1851-7⟩. ⟨hal-01319445⟩
    • Dimitrios Bitounis, Jérémie Pourchez, Valérie Forest, Delphine Boudard, Michèle Cottier, et al.. Detection and analysis of nanoparticles in patients: A critical review of the status quo of clinical nanotoxicology. Biomaterials, 2016, 76, pp.302-312. ⟨10.1016/j.biomaterials.2015.10.061⟩. ⟨hal-01320283⟩
    • Lara Leclerc, Jean-Philippe Klein, Valérie Forest, Delphine Boudard, Matteo Martini, et al.. Testicular biodistribution of silica-gold nanoparticles after intramuscular injection in mice. Biomedical Microdevices, 2015, 17 (4), pp.9968. ⟨10.1007/s10544-015-9968-3⟩. ⟨hal-01216399⟩
    • Valérie Forest, Michèle Cottier, Jérémie Pourchez. Electrostatic interactions favor the binding of positive nanoparticles on cells: a reductive theory. Nano Today, 2015, 10 (6), pp.677-680. ⟨10.1016/j.nantod.2015.07.002⟩. ⟨hal-01891015⟩
    • Lara Leclerc, Amira El Merhie, Laurent Navarro, Nathalie Prévôt, Marc Durand, et al.. Impact of acoustic airflow on intrasinus drug deposition: New insights into the vibrating mode and the optimal acoustic frequency to enhance the delivery of nebulized antibiotic. International Journal of Pharmaceutics, 2015, 494 (1), pp.227-234. ⟨10.1016/j.ijpharm.2015.08.025⟩. ⟨hal-01272228⟩
    • Andréa Kurtz-Chalot, Jean-Philippe Klein, Jérémie Pourchez, Delphine Boudard, Valérie Bin, et al.. Quantification of nanoparticle endocytosis based on double fluorescent pH-sensitive nanoparticles. Biomedical Microdevices, 2015, 17 (2), pp.42. ⟨10.1007/s10544-015-9947-8⟩. ⟨hal-01215438⟩
    • Agathe Figarol, Jérémie Pourchez, Delphine Boudard, Valérie Forest, Sarah Berhanu, et al.. Thermal annealing of carbon nanotubes reveals a strong toxicological impact of the structural defects. Journal of Nanoparticle Research, 2015, 17 (4), pp.article 194. ⟨10.1007/s11051-015-2999-0⟩. ⟨emse-01148477v2⟩
    • L. Rinaldi, G. Barabino, J.-P. Klein, D. Bitounis, J. Pourchez, et al.. Metals distribution in colorectal biopsies: New insight on the elemental fingerprint of tumour tissue. Digestive and Liver Disease, 2015, 47 (7), pp.602-607. ⟨10.1016/j.dld.2015.03.016⟩. ⟨hal-01215476⟩
    • Agathe Figarol, Jérémie Pourchez, Delphine Boudard, Valérie Forest, Céline Akono, et al.. In vitro toxicity of carbon nanotubes, nano-graphite and carbon black, similar impacts of acid functionalization. Toxicology in Vitro, 2015, 30 (1 Part B), pp.476-485. ⟨10.1016/j.tiv.2015.09.014⟩. ⟨emse-01212432⟩
    • Valérie Forest, Agathe Figarol, Delphine Boudard, Michèle Cottier, Philippe Grosseau, et al.. Adsorption of lactate dehydrogenase enzyme on carbon nanotubes: how to get accurate results about the cytotoxicity of these nanomaterials. Langmuir, 2015, 31 (12), pp.3635-3643. ⟨10.1021/acs.langmuir.5b00631⟩. ⟨hal-01133372⟩
    • Lara Leclerc, Jérémie Pourchez, Gérald Aubert, Sandrine Leguellec, Laurent Vecellio, et al.. Impact of Airborne Particle Size, Acoustic Airflow and Breathing Pattern on Delivery of Nebulized Antibiotic into the Maxillary Sinuses Using a Realistic Human Nasal Replica. Pharmaceutical Research, 2014, 31 (9), pp.2335-2343. ⟨10.1007/s11095-014-1330-6⟩. ⟨emse-01110944⟩
    • Iolanda M.D. Albuquerque-Silva, Laurent Vecellio, Marc Durand, John Avet, Deborah Le Pennec, et al.. Particle Deposition in a Child Respiratory Tract Model: In Vivo Regional Deposition of Fine and Ultrafine Aerosols in Baboons. PLoS ONE, 2014, 9 (4), pp.e95456. ⟨10.1371/journal.pone.0095456⟩. ⟨hal-01017463⟩
    • Delphine Boudard, Valérie Forest, Jérémie Pourchez, Najih Boumahdi, Maura Tomatis, et al.. In vitro cellular responses to silicon carbide particles manufactured through the Acheson process: impact of physico-chemical features on pro-inflammatory and pro-oxidative effects.. Toxicology in Vitro, 2014, 28 (5), pp.856-865. ⟨10.1016/j.tiv.2014.02.012⟩. ⟨hal-01021766⟩
    • Agathe Figarol, Jérémie Pourchez, Delphine Boudard, Valérie Forest, Jean-Marc Tulliani, et al.. Biological response to purification and acid functionalization of carbon nanotubes. Journal of Nanoparticle Research, 2014, 16, pp.2507. ⟨10.1007/s11051-014-2507-y⟩. ⟨hal-01017203⟩
    • Andréa Kurtz-Chalot, Jean-Philippe Klein, Jérémie Pourchez, Delphine Boudard, Valérie Bin, et al.. Adsorption at cell surface and cellular uptake of silica nanoparticles with different surface chemical functionalizations: impact on cytotoxicity. Journal of Nanoparticle Research, 2014, 16 (11), pp.2738. ⟨10.1007/s11051-014-2738-y⟩. ⟨hal-01215292⟩
    • Sandrine Le Guellec, Deborah Le Pennec, Stéphane Gatier, Lara Leclerc, Maria Cabrera, et al.. Validation Of Anatomical Models To Study Aerosol Deposition In Human Nasal Cavities. Pharmaceutical Research, 2014, 31 (1), pp.228-237. ⟨10.1007/s11095-013-1157-6⟩. ⟨hal-01139263⟩
    • Valérie Forest, Mélanie Pailleux, Jérémie Pourchez, Delphine Boudard, Maura Tomatis, et al.. Toxicity of boehmite nanoparticles: impact of the ultrafine fraction and of the agglomerates size on cytotoxicity and pro-inflammatory response. Inhalation Toxicology, 2014, 26 (9), pp.545-553. ⟨10.3109/08958378.2014.925993⟩. ⟨hal-01020274⟩
    • Lara Leclerc, Jérémie Pourchez, Nathalie Prevot, Laurent Vecellio, Sandrine Le Guellec, et al.. Assessing sinus aerosol deposition: benefits of SPECT-CT imaging. International Journal of Pharmaceutics, 2014, 462 (1-2), pp.135-141. ⟨10.1016/j.ijpharm.2013.12.032⟩. ⟨hal-01019021⟩
    • P. Le Guen, N. Peron, M. Durand, J. Pourchez, P. Cavaillon, et al.. Inhalation therapy: Inhaled corticosteroids in ENT, development and technical challenges of powder inhalers, nebulisers synchronized with breathing and aerosol size distribution. Revue des Maladies Respiratoires, 2013, 30 (8), pp.657-668. ⟨10.1016/j.rmr.2013.09.006⟩. ⟨hal-01139226⟩
    • Jean-Philippe Klein, Delphine Boudard, Josette Cadusseau, Sabine Palle, Valérie Forest, et al.. Testicular biodistribution of 450 nm fluorescent latex particles after intramuscular injection in mice.. Biomedical Microdevices, 2013, 15 (3), pp.427-36. ⟨10.1007/s10544-013-9741-4⟩. ⟨hal-00833864⟩
    • Jérémie Pourchez, Iolanda M.D. Albuquerque-Silva, Michèle Cottier, Anthony Clotagatide, Laurent Vecellio, et al.. Generation and characterization of radiolabelled nanosized carbonaceous aerosols for human inhalation studies. Journal of Aerosol Science, 2013, 55, pp.1-11. ⟨10.1016/j.jaerosci.2012.07.011⟩. ⟨hal-00734617⟩
    • Wael Rima, Lucie Sancey, Marie-Thérèse Aloy, Emma Armandy, B. Alcantara Gustavo, et al.. Internalization pathways into cancer cells of gadolinium-based radiosensitizing nanoparticles. Biomaterials, 2013, 34, pp.181-195. ⟨10.1016/j.biomaterials.2012.09.029⟩. ⟨hal-00757773⟩
    • Mélanie Pailleux, Delphine Boudard, Jérémie Pourchez, Valérie Forest, Philippe Grosseau, et al.. New insight into artifactual phenomena during in vitro toxicity assessment of engineered nanoparticles: Study of TNF-α adsorption on alumina oxide nanoparticle. Toxicology in Vitro, 2013, 27, pp.1049-1056. ⟨10.1016/j.tiv.2013.01.022⟩. ⟨hal-00799129⟩
    • Marc Durand, Sandrine Le Guellec, Jérémie Pourchez, Francis Dubois, Gérald Aubert, et al.. Démonstration du ciblage des sinus maxillaires par aérosolthérapie sonique. Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, 2012, 129 (5), pp.288-295. ⟨10.1016/j.aforl.2011.12.002⟩. ⟨hal-00757521⟩
    • Sandrine Le Guellec, Marc Durand, Jérémie Pourchez, Francis Dubois, Gérard Aubert, et al.. Evaluation of the performance of sonic nebuliser to target maxillary sinuses. Journal of Cystic Fibrosis, 2012, 11 (S1), pp.S53. ⟨10.1016/S1569-1993(12)60166-0⟩. ⟨hal-00734297⟩
    • Lara Leclerc, Wael Rima, Delphine Boudard, Jérémie Pourchez, Valérie Forest, et al.. Size of submicrometric and nanometric particles affect cellular uptake and biological activity of macrophages in vitro. Inhalation Toxicology, 2012, 24 (9), pp.580-588. ⟨10.3109/08958378.2012.699984⟩. ⟨hal-00733900⟩
    • Lara Leclerc, Delphine Boudard, Jérémie Pourchez, Valérie Forest, Laurence Marmuse, et al.. Quantitative cellular uptake of double fluorescent core-shelled model submicronic particles. Journal of Nanoparticle Research, 2012, 14 (11), pp.14 :1221. ⟨10.1007/s11051-012-1221-x⟩. ⟨hal-00757737⟩
    • Jérémie Pourchez, Valérie Forest, Najih Boumahdi, Delphine Boudard, Maura Tomatis, et al.. In vitro cellular responses to silicon carbide nanoparticles: impact of physico-chemical features on pro-inflammatory and pro-oxidative effects. Journal of Nanoparticle Research, 2012, 14 (10), pp.1143. ⟨10.1007/s11051-012-1143-7⟩. ⟨hal-00734434⟩
    • Marc Durand, Sandrine Le Guellec, Jérémie Pourchez, Francis Dubois, Gérald Aubert, et al.. Sonic aerosol therapy to target maxillary sinuses. European Archives of Oto-Rhino-Laryngology, 2012, 129 (5), pp.244-250. ⟨10.1016/j.anorl.2011.09.002⟩. ⟨hal-00757723⟩
    • Marc Durand, Jérémie Pourchez, Bruno Louis, Jean-François Pouget, Daniel Isabey, et al.. Plastinated nasal model: a new concept of anatomically realistic cast.. Rhinology, 2011, 49 (1), pp.30-6. ⟨10.4193/Rhino09.187⟩. ⟨hal-00583950⟩
    • Marc Durand, Jérémie Pourchez, Gérald Aubert, Sandrine Le Guellec, Laurent Navarro, et al.. Impact of acoustic airflow nebulization on intrasinus drug deposition of a human plastinated nasal cast: New insights into the mechanisms involved. International Journal of Pharmacy, 2011, 421 (1), pp.63-71. ⟨10.1016/j.ijpharm.2011.09.023⟩. ⟨hal-00640705⟩
    • Lara Leclerc, Delphine Boudard, Jérémie Pourchez, Valérie Forest, Laurence Marmuse, et al.. Development of innovative pH sensor nanoparticles: a new approach to evaluate phagocytosis. Bulletin du Cancer, 2011, 98, pp.S65-S66. ⟨emse-00583357⟩
    • Mélanie Pailleux, Jérémie Pourchez, Delphine Boudard, Philippe Grosseau, Michèle Cottier. Study of the toxicity of inhaled ultrafine engineered powder: example of boehmite nanoparticles. Bulletin du Cancer, 2011, 98, pp.S66-S67. ⟨emse-00583237⟩
    • Lara Leclerc, Delphine Boudard, Jérémie Pourchez, Sabine Palle, Philippe Grosseau, et al.. Development of innovative pH sensor to evaluate phagocytosis of nanoparticles. Bulletin du Cancer, 2010, 97, pp.S15-S16. ⟨emse-00581050⟩
    • Lara Leclerc, Delphine Boudard, Jérémie Pourchez, Valérie Forest, Odile Sabido, et al.. Quantification of microsized fluorescent particles phagocytosis to a better knowledge of toxicity mechanisms. Inhalation Toxicology, 2010, 22 (13), pp.1091-1100. ⟨10.3109/08958378.2010.522781⟩. ⟨hal-00550956⟩
    • Jérémie Pourchez, Bertrand Ruot, Johan Debayle, Emilie Rouèche-Pourchez, Philippe Grosseau. Some aspects of cellulose ethers influence on water transport and porous structure of cement-based materials. Cement and Concrete Research, 2010, 40 (2), pp.242-252. ⟨10.1016/j.cemconres.2009.10.008⟩. ⟨hal-00464184⟩
    • Mélanie Pailleux, Jérémie Pourchez, Philippe Grosseau, Delphine Boudard, Michèle Cottier. Toxicity assessment of nanoparticles: impact of physico-chemical properties and adsorption artefacts on biological responses. Bulletin du Cancer, 2010, 97, pp.S18. ⟨emse-00583184⟩
    • Jérémie Pourchez, Philippe Grosseau, Bertrand Ruot. Changes in C3S hydration in presence of cellulose ethers. Cement and Concrete Research, 2010, 40 (2), pp.179-188. ⟨10.1016/j.cemconres.2009.10.008⟩. ⟨hal-00463071⟩
    • Jérémie Pourchez, Philippe Grosseau, Bernard Ruot. Current understanding of cellulose ethers impact on the hydration of C3A and C3A-sulphate systems. Cement and Concrete Research, 2009, 39 (8), pp.664-669. ⟨10.1016/j.cemconres.2009.05.009⟩. ⟨hal-00409937⟩
    • Mélanie Pailleux, Najih Boumahdi, Jérémie Pourchez, Philippe Grosseau, Delphine Boudard, et al.. Étude de la toxicité par inhalation de poudres industrielles ultrafines. Bulletin du Cancer, 2009, 96, pp.S5. ⟨emse-00583166⟩
    • Lara Leclerc, Delphine Boudard, Odile Sabido, Valérie Bin, Sabine Palle, et al.. Modèle de quantification de la phagocytose à partir de particules fluorescentes. Bulletin du Cancer, 2009, 96, pp.S9. ⟨emse-00581060⟩
    • Laetitia Patural, Philippe Grosseau, Alexandre Govin, Jérémie Pourchez, Bertrand Ruot. Water transport in freshly-mixed mortars containing cellulose ethers. Journal du CEREM, 2008. ⟨emse-00517893⟩
    • A. Peschard, A. Govin, J. Pourchez, E. Fredon, Lionel Bertrand, et al.. Effect of polysaccharides on the hydration of cement suspension. Journal of the European Ceramic Society, 2006, pp.1439-1445. ⟨hal-00436162⟩
    • Jérémie Pourchez, Philippe Grosseau, René Guyonnet, Bertrand Ruot. HEC influence on cement hydration measured by conductometry. Cement and Concrete Research, 2006, 36 (9), pp.1777-1780. ⟨10.1016/j.cemconres.2006.06.002⟩. ⟨emse-00449716⟩
    • Jérémie Pourchez, Arnaud Peschard, Philippe Grosseau, René Guyonnet, Bernard Guilhot, et al.. HPMC and HEMC influence on cement hydration. Cement and Concrete Research, 2006, 36 (2), pp.288-294. ⟨10.1016/j.cemconres.2005.08.003⟩. ⟨emse-00449706⟩
    • Jérémie Pourchez, Françoise Valdivieso, Philippe Grosseau, Alexandre Govin, Bernard Guilhot. Kinetic modelling of the thermal decomposition of ettringite into metaettringite. Cement and Concrete Research, 2006, 36 (11), pp.2054-2060. ⟨10.1016/j.cemconres.2006.06.007⟩. ⟨emse-00449727⟩
    • Jérémie Pourchez, Alexandre Govin, Philippe Grosseau, René Guyonnet, Bernard Guilhot, et al.. Alkaline stability of cellulose ethers and impact of their degradation products on cement hydration. Cement and Concrete Research, 2006, 36 (7), pp.1252-1256. ⟨10.1016/j.cemconres.2006.03.028⟩. ⟨emse-00449712⟩

    Conference papers24 document

    • Bogdan Muresan, Xuan-Trinh Truong, Tiago De Oliveira, Louisa Landebrit, Valérie Forest, et al.. Reducing the impact of TRWP emissions by understanding their nature and environmental dynamics. Tackling Tire Wear and Associated Chemical Risks, Environment Agency Austria on behalf of the Austrian Ministry of Agriculture and Forestry, Climate and Environmental Protection, Regions and Water Management., Nov 2025, Vienne (Austria), Austria. ⟨hal-05391913⟩
    • Claire Longuet, Carine Chivas-Joly, Valérie Forest, Jérémie Pourchez, Sébastien Moussard, et al.. Human exposure related to nano or microplastics during recycling process. MICRO 2024 - 5th International Conference : Plastic Pollution from Macro to Nano, Sep 2024, Lanzarote, Spain. ⟨hal-04748226⟩
    • Bogdan Muresan, Valérie Forest, Tiago De Oliveira, Xuan-Trinh Truong, Laurence Lumiere, et al.. Émissions hors échappement du contact pneu-chaussée: dynamiques d'émission, propriétés physico-chimiques et effets cellulaires. Journées scientifiques Nantes Université, Nantes Université, Jun 2024, Nantes, France. ⟨hal-04595725⟩
    • E. Bougart, L. Leclerc, J. Pourchez, M. Sleiman. Characterization of nicotine salts In E-Liquids and E-Cigarette aerosols.. 21st European Meeting on Environmental Chemistry (EMEC21), Nov 2021, Novi Sad, Serbia. ⟨hal-03572995⟩
    • Jérémie Pourchez, Valérie Forest. Design physico-chimique des nanoparticules et internalisation cellulaire. Matériaux 2014, Fédération Française des Matériaux (FFM), Nov 2014, Montpellier, France. ⟨hal-01272911⟩
    • Agathe Figarol, Jérémie Pourchez, Delphine Boudard, Valérie Forest, Jean-Marc Tulliani, et al.. Biological response to purification and acid functionalization of carbon nanotubes. 4TH International conference on Safe production and use of nanomaterials, MINATEC; CEA Grenoble, Nov 2014, Grenoble, France. p. 101. ⟨emse-01109440⟩
    • D. Bitounis, C. Guibert, Valérie Forest, Delphine Boudard, Jérémie Pourchez, et al.. Towards an indicator of nanomaterial deposition in the human lung Nanotubes. International Conference on Safe Production and Use of Nanomaterials (NANOSAFE 2014), Nov 2014, Grenoble, France. ⟨hal-01216700⟩
    • Lara Leclerc, Jérémie Pourchez, Sophie Ragey, Nathalie Prevot, Michèle Cottier, et al.. Development of Alternative Models to In Vivo Animal Human Experiments for Regional Aerosol Deposition. Second Aerosol Dosimetry Conference, Oct 2014, Irvine, United States. ⟨hal-01216693⟩
    • Agathe Figarol, Jérémie Pourchez, Delphine Boudard, Valérie Forest, Jean-Marc Tulliani, et al.. Control of Carbon Nanotubes Biological Activity by Acid Functionalization: a Janus Impact on In Vitro Cellular Response. NANOSMAT USA, May 2014, Houston, United States. ⟨hal-01052745⟩
    • Andréa Kurtz-Chalot, Valérie Forest, Jérémie Pourchez, Delphine Boudard, Valérie Bin, et al.. Uptake and cytotoxicity of silica nanoparticles with different surface functionalizations. E-MRS 2013 Spring Meeting, May 2013, Strasbourg, France. ⟨hal-00861784⟩
    • Agathe Figarol, Jérémie Pourchez, Delphine Boudard, Valérie Forest, Jean-Marc Tulliani, et al.. Nanotubes de carbone fonctionnalisés : caractérisation physico-chimique et toxicité in vitro. Colloque PMF 2013, Poudres et matériaux frittés, May 2013, Belfort, France. ⟨hal-01052911⟩
    • Andréa Kurtz-Chalot, Valérie Forest, Jérémie Pourchez, Delphine Boudard, Valérie Bin, et al.. Uptake and cytotoxicity of silica nanoparticles with different surface functionalizations. Colloque Nanohybrides 10, May 2013, Porquerolles, France. ⟨hal-00861420⟩
    • Lara Leclerc, Jérémie Pourchez, Gérald Aubert, Laurent Vecellio, Marc Durand. Impact of MMAD, acoustic airflow and breathing patterns on intrasinus drug deposition in a realistic nasal cast. International Society for Aerosols in Medecine (ISAM 2013), Apr 2013, Chapel Hill, United States. ⟨hal-01216661⟩
    • Andréa Kurtz-Chalot, Valérie Forest, Jérémie Pourchez, Delphine Boudard, Valérie Bin, et al.. Uptake and cytotoxicity of silica nanoparticles with different surface functionalizations. 8èmes Journées Scientifiques du CLARA, Mar 2013, Lyon, France. ⟨hal-00861811⟩
    • Muriel Dubosson, Caroline Desvergne, Véronique Mossuz, Michèle Cottier, Jérémie Pourchez, et al.. Is exhaled breath condensate representative of deep lung and suitable for exposure assessment to nanoparticles?. International Conference on Safe Production and Use of Nanomaterials (Nanosafe 2012), Nov 2012, Grenoble, France. ⟨hal-00777295⟩
    • Jérémie Pourchez, I. F. M. Albuquerque, Marc Durand, J. Avet, D. Le Penec, et al.. In vivo regional deposition of submicronic-sized airborne particles in the baboon respiratory model. EAC 2012 'European Aerosol Conference ), Sep 2012, Grenade, Spain. ⟨hal-00778311⟩
    • Marc Durand, Jérémie Pourchez, Sandrine Le Guellec, Gérald Aubert, Bruno Louis, et al.. Acoustic airflow nebulization on intrasinus drug deposition in a new concept of nasal cast: the human plastinated head model. 24th European Rhinology Society, Jun 2012, Toulouse, France. ⟨hal-00777414⟩
    • Gabriele Barabino, Michèle Cottier, Jérémie Pourchez, Delphine Boudard, Xavier Roblin, et al.. Nanoparticules et dépistage du cancer colorectal : application humaine ex-vivo. JFHOD (Journées Francophones d'Hépato-gastroentérologie et d'Oncologie Digestive), Mar 2012, Paris, France. ⟨hal-00779225⟩
    • Iolanda Albuquerque, Jérémie Pourchez, Laurent Vecellio, Didier Bernache-Assollant, Francis Dubois. Nébuliseur nanométrique : potentiel d’un nouveau dispositif pour la scintigraphie de ventilation. Congrès Français des Aérosols, Jan 2011, Paris, France. ⟨hal-01286707⟩
    • Mélanie Pailleux, Jérémie Pourchez, Delphine Boudard, Philippe Grosseau, Michèle Cottier. Study on the toxicity of inhaled alumina nanoparticles: impact of physicochemical properties and adsorption artifacts on the measurement of biological responses. International Conference on Safe Production and Use of Nanomaterials, Nanosafe 2010, Nov 2010, Grenoble, France. pp.012041, ⟨10.1088/1742-6596/304/1/012041⟩. ⟨hal-00607318⟩
    • Lara Leclerc, Delphine Boudard, Jérémie Pourchez, Odile Sabido, Sabine Palle, et al.. Development of innovative methods for phagocytosis quantification of microsized particles.. AFC & ESFCCA 2009 (Association Française de Cytométrie & European Society for Clinical Cell Analysis), Sep 2009, Saint Etienne, France. ⟨emse-00601465⟩
    • Jérémie Pourchez, Philippe Grosseau, René Guyonnet, Bertrand Ruot. Impact des éthers de cellulose sur l'hydratation du silicate tricalcique. XI° Congrès de la Société Française de Génie des Procédés. Des réponses industrielles pour une société en mutation., Oct 2007, Saint Etienne, France. pp.ISBN=2-910239-70-5. ⟨hal-00457814⟩
    • Jérémie Pourchez, Philippe Grosseau, Emilie Rouèche-Pourchez, Johan Debayle, Jean-Charles Pinoli, et al.. Impact of cellulose ethers on the cement paste microstructure. 10th International Conference and Exhibition of the European Ceramic Society, Jun 2007, Berlin, Germany. pp.2045-2050. ⟨hal-00297256⟩
    • Elodie Boller, Peter Cloetens, José Baruchel, Paul Tafforeau, Olivier Rozenbaum, et al.. Synchrotron X-Ray microtomography: a high resolution, fast and quantitative tool for rock characterization.. 2006, 9p. ⟨hal-00101634⟩

    Poster communications1 document

    • Agathe Figarol, Jérémie Pourchez, Delphine Boudard, Valérie Forest, Jean-Marc Tulliani, et al.. Activité biologique de nanotubes de carbone : fonctionnalisation acide. Matériaux 2014, Nov 2014, Montpellier, France. . ⟨emse-01102912⟩

    Other publications1 document

    • Anne Pasquereau, Guillemette Quatremere, Romain Guignard, Raphael Andler, Florian Verrier, et al.. E-CIGARETTE Usage de la cigarette électronique, tabagisme et opinion des 18-75 ans.. 2019. ⟨hal-02178086⟩

    Reports4 document

    • Michel Guerbet, Sébastien Anthérieu, Stéphanie Caillé-Garnier, Dominique Guenot, Shérazade Kinouani, et al.. Étude sur les pratiques de consommation des usagers de cigarettes électroniques en France - Appui à la caractérisation des expositions. Saisine n°2020-SA-0017, Anses. 2022, 64 p. ⟨anses-04165768⟩
    • Michel Guerbet, Laurent Boyer, Stéphanie Caillé-Garnier, Hervé Casabianca, Nicolas Concha Lozano, et al.. Critères, échantillonnage et méthodes analytiques pour la surveillance et le contrôle de la conformité règlementaire des produits du tabac et produits du
      vapotage sur le marché français. Saisine n° 2020-SA-0015, Anses. 2022, 120 p. ⟨anses-04016271⟩
    • Michel Guerbet, Laurent Boyer, Stéphanie Caillé-Garnier, Hervé Casabianca, Nicolas Concha Lozano, et al.. Priorisation des substances chimiques à rechercher dans les émissions des produits du vapotage en vue de l’évaluation des risques sanitaires. Saisine n° 2020-SA-0016, Anses. 2021, 57 p. ⟨anses-03890262⟩
    • David Vernez, Sandrine Chazelet, Nicolas Eterradossi, Francois Gaie-Levrel, Jean François Gehanno, et al.. Avis de l'Anses relatif à « l’élaboration d’un référentiel des exigences pour les procédés de traitement de masques chirurgicaux, FFP et équivalents en vue de leur réutilisation ». Saisine n°2020-SA-0075, Anses. 2020, 26 p. ⟨anses-04302687⟩

    Theses1 document

    • Jérémie Pourchez. Aspects physico-chimiques de l'interaction des éthers de cellulose avec la matrice cimentaire. Génie des procédés. Ecole Nationale Supérieure des Mines de Saint-Etienne, 2006. Français. ⟨NNT : ⟩. ⟨tel-00122935⟩

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    Career

    Career

    CURRENT POSITIONS
    Since 2013 Full-Professor in aerosol science and inhalation toxicology, Center for Biomedical and Healthcare Engineering, Mines Saint-Etienne/ARMINES Common Research Centre, France

    PREVIOUS POSITIONS
    2007-2012 Associate Professor in aerosol science and inhalation toxicology, Center for Biomedical and Healthcare Engineering, Mines Saint-Etienne, France

    Distinctions

    Awards & Distinctions

    FELLOWSHIPS AND AWARDS
    2017-2020 ANR Young Researcher GRANT : “AMADEUS project” – Anatomical Models to study Aerosol DElivery to the lUngS for obstructive diseases
    2014-2016 Institut Mines-Telecom Investigator Grant, ROQSTAR project focusing on in silico modelling (QSAR) for inhalation toxicology of nanoparticles
    2011-2013 ARAIR Investigator Grant, AERONANO project (ARAIR: association for patients with respiratory failure) to develop innovative submicron-sized nebulizer
    Jan-April 2007 Visiting fellow, Politechnico di Torino, Italia

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