Research

Centre for Biomedical and Healthcare Engineering

“Improving health through Science and Engineering”

Head

Vincent Augusto
vincent.augusto@mines-stetienne.fr

Research Fields

  • Biomechanics of soft tissues, medical textiles and implants
  • Engineering of biomaterials and inhaled particles
  • Engineering of care structures and health systems

Fields of Expertise

  • Biomedical (ageing, tissue engineering…), surgery (orthopaedic, vascular), ealthcare (oncology, infectiology…), organization (hospital logistics).

Human Resources

70 persons

  • 30 permanent faculty and staff
  • 40 PhD Students and Post-PhD Researchers

Industrial sectors

  • Biomedical devices, augmented medicine
  • Pharmacy, healthcare systems
  • Sports industry, cosmetics

Research units

Scientific Departments

STBio – Soft Tissue BIOmechanics

Contact: Jerôme Molimard, jerome.molimard@mines-stetienne.fr

  • Prevention of aneurysm ruptures
  • Biomechanical action of medical textiles
  • Numerical simulations
  • Biotribocorrosion of implants

I4S – Healthcare Engineering

Contact: Xiaolan Xie, xiaolan.xie@mines-stetienne.fr

  • Modelling,
  • Simulation and optimization of healthcare systems
  • Planning
  • Hospital logistics
  • Operational research

BioPI – Biological Activity of inhaled NanoParticles

Contact: Valérie Forestvalerie.forest@mines-stetienne.fr

  • Toxicity of nano and micrometric particles
  • Aerosol metrology
  • Detection of particles in biological samples from patients
  • Medical devices for aerosoltherapy
  • E-cigarette for smoking cessation (characterization of emissions, toxicology…)
  • Bio-physico-chemical characterization of materials

BioMat – Biomaterials Engineering

Contact: David Eglindavid.eglin@mines-stetienne.fr

  • Synthesis and manufacturing of bioceramics
  • In vitro bone tissue models
  • Development of bioinstructive materials for understanding mechanisms
  • Study of the behavior and aging of orthopedic implants (Fatigue testing)

A technological Platform: #FutureMedicine

6 Technical Space Facilities

3DFabLab

Contact: David Marchat, david.marchat@mines-stetienne.fr

Tribocorrosion/Orthopedic Implants

Contact: Jean Geringer, jean.geringer@mines-stetienne.fr

Artificial Intelligence Laboratory

Contact: Laurent Navarro, laurent.navarro@mines-stetienne.fr

Biomechanical Tests

Contact: Baptiste Pierrat, baptiste.pierrat@mines-stetienne.fr

Poster (PDF)

Expertise
  • Mechanical characterization of soft tissues and textiles
    • Constitutive data characterization (Elastic modulus, Visco-elasticity, Anisotropy, Damage, …)
    • Fatigue testing
      Experience with biological tissues: arterial wall, linea alba, tendons, ligaments, skin, …
  • Evaluation of medical devices and sport equipment
    • 3D full field measurements: shapes, displacement and strain maps
    • Interface pressure measurements
    • In-silico evaluation of body/device mechanical interactions
  • Numerical simulation
    • Model generation from medical images
    • Non-linear finite element analysis
    • Solid mechanics, CFD
    • Parametric analyses
    • Constitutive model development and implementation
Equipment
  • Mechanical testing
    Electroforce biaxial test bench, Instron uniaxial tensile testing machine, FSA pressure mapping system…
  • Optical systems
    Stereo-correlation bench (with inflation test), fringe projection system, OCT, microscopes…
  • ​Softwares
    Finite element (Abaqus, Ansys, FEBio), Image processing (Simpleware, ImageJ), Numerical computing (Matlab), System-design (Labview, Arduino)
  • Computer cluster for parallel computing
​Applications
  • Cardiovascular biomechanics
    Patient-specific computer simulations for planning endovascular repairs
    Characterization of the rupture mechanisms of abdominal aortic aneurysms…
  • Musculoskeletal biomechanics
    Investigation of pressure applied by lumbar belts
    Evaluation of the mechanical effect of knee braces

Virtual Hospital: A Digital Twin

Contact: Raksmey Phan, raksmey.phan@mines-stetienne.fr

  • Discrete event simulation of care pathways
  • Healthcare resource planning
  • Healthcare process design
  • Healthcare data analytics
  • Cluster computers (or High-Performance Computing) and application server

Inhaled Particles (Aerosoltherapy, Toxicity)

Contact: Lara Leclerc, lara.leclerc@mines-stetienne.fr

  • Synthesis (semi-industrial production), advanced shaping (tailor-made) and characterization of calcium phosphates bioceramics for bone tissue engineering.
    Applications: Development of calcium phosphates biomaterials and innovative (manufacturing) process, fabrication of functional prototypes and supporting companies in innovation and project set-up at industrial scale.
    Poster (PDF)
  • Aerosol generation and characterization – Deposition studies on anatomical models.
    Applications: Medical devices for aerosoltherapy, bioaerosols and e-cigarette for smoking cessation.
    Poster (PDF)
  • Nanoparticles detection and physico-chemical characterization in biological samples – In vitro biological activity evaluation – Air-liquid interface exposure (Vitrocell).
    Applications: Industrial nanotoxicology, mineralopathology.
    Poster (PDF)