“Improving health through Science and Engineering”
Head
Vincent Augusto
vincent.augusto@mines-stetienne.fr
Research Fields
- Biomechanics of soft tissues, medical textiles and implants
- Engineering of biomaterials and inhaled particles
- Engineering of care structures and health systems
Fields of Expertise
- Biomedical (ageing, tissue engineering…), surgery (orthopaedic, vascular), ealthcare (oncology, infectiology…), organization (hospital logistics).
Human Resources
70 persons
- 30 permanent faculty and staff
- 40 PhD Students and Post-PhD Researchers
Industrial sectors
- Biomedical devices, augmented medicine
- Pharmacy, healthcare systems
- Sports industry, cosmetics
Research units
- SaInBioSE (INSERM U1059)
- LIMOS (CNRS UMR 6158)
- UR hosted by Sentinels Network (Réseau Sentinelles) (INSERM U707 Sorbonne University)
Scientific Departments
STBio – Soft Tissue BIOmechanics
Contact: Jerôme Molimard, jerome.molimard@mines-stetienne.fr
- Prevention of aneurysm ruptures
- Biomechanical action of medical textiles
- Numerical simulations
- Biotribocorrosion of implants
I4S – Healthcare Engineering
Contact: Xiaolan Xie, xiaolan.xie@mines-stetienne.fr
- Modelling,
- Simulation and optimization of healthcare systems
- Planning
- Hospital logistics
- Operational research
BioPI – Biological Activity of inhaled NanoParticles
Contact: Valérie Forest, valerie.forest@mines-stetienne.fr
- Toxicity of nano and micrometric particles
- Aerosol metrology
- Detection of particles in biological samples from patients
- Medical devices for aerosoltherapy
- E-cigarette for smoking cessation (characterization of emissions, toxicology…)
- Bio-physico-chemical characterization of materials
BioMat – Biomaterials Engineering
Contact: David Eglin, david.eglin@mines-stetienne.fr
- Synthesis and manufacturing of bioceramics
- In vitro bone tissue models
- Development of bioinstructive materials for understanding mechanisms
- Study of the behavior and aging of orthopedic implants (Fatigue testing)
A technological Platform: #FutureMedicine
6 Technical Space Facilities
3DFabLab
Contact: David Marchat, david.marchat@mines-stetienne.fr
Tribocorrosion/Orthopedic Implants
Contact: Jean Geringer, jean.geringer@mines-stetienne.fr
Artificial Intelligence Laboratory
Contact: Laurent Navarro, laurent.navarro@mines-stetienne.fr
Biomechanical Tests
Contact: Baptiste Pierrat, baptiste.pierrat@mines-stetienne.fr
Expertise
- Mechanical characterization of soft tissues and textiles
- Constitutive data characterization (Elastic modulus, Visco-elasticity, Anisotropy, Damage, …)
- Fatigue testing
Experience with biological tissues: arterial wall, linea alba, tendons, ligaments, skin, …
- Evaluation of medical devices and sport equipment
- 3D full field measurements: shapes, displacement and strain maps
- Interface pressure measurements
- In-silico evaluation of body/device mechanical interactions
- Numerical simulation
- Model generation from medical images
- Non-linear finite element analysis
- Solid mechanics, CFD
- Parametric analyses
- Constitutive model development and implementation
Equipment
- Mechanical testing
Electroforce biaxial test bench, Instron uniaxial tensile testing machine, FSA pressure mapping system… - Optical systems
Stereo-correlation bench (with inflation test), fringe projection system, OCT, microscopes… - Softwares
Finite element (Abaqus, Ansys, FEBio), Image processing (Simpleware, ImageJ), Numerical computing (Matlab), System-design (Labview, Arduino) - Computer cluster for parallel computing
Applications
- Cardiovascular biomechanics
Patient-specific computer simulations for planning endovascular repairs
Characterization of the rupture mechanisms of abdominal aortic aneurysms… - Musculoskeletal biomechanics
Investigation of pressure applied by lumbar belts
Evaluation of the mechanical effect of knee braces
Virtual Hospital: A Digital Twin
Contact: Raksmey Phan, raksmey.phan@mines-stetienne.fr
- Discrete event simulation of care pathways
- Healthcare resource planning
- Healthcare process design
- Healthcare data analytics
- Cluster computers (or High-Performance Computing) and application server
Inhaled Particles (Aerosoltherapy, Toxicity)
Contact: Lara Leclerc, lara.leclerc@mines-stetienne.fr
- Synthesis (semi-industrial production), advanced shaping (tailor-made) and characterization of calcium phosphates bioceramics for bone tissue engineering.
Applications: Development of calcium phosphates biomaterials and innovative (manufacturing) process, fabrication of functional prototypes and supporting companies in innovation and project set-up at industrial scale.
Poster (PDF) - Aerosol generation and characterization – Deposition studies on anatomical models.
Applications: Medical devices for aerosoltherapy, bioaerosols and e-cigarette for smoking cessation.
Poster (PDF) - Nanoparticles detection and physico-chemical characterization in biological samples – In vitro biological activity evaluation – Air-liquid interface exposure (Vitrocell).
Applications: Industrial nanotoxicology, mineralopathology.
Poster (PDF)