Claudie PETIT

  • Responsibilities and Duties

    Duties :

    -2017/2020 : PhD thesis : Experimental work at cellular/subcellular scale aiming to characterize the biomechanical role of Smooth Muscle Cells (SMCs) from aortic tissue => Fluorescent Microscopy (FM), Atomic Force Microscopy (AFM), Traction Force Microscopy (TFM), cell culture (human SMCs), primary culture of SMCs from human aneurysm.
    -2016/2017 : End-of-studies project : Development of several experimental protocols for the combination of FM and AFM on animal single cells fixed on adhesive micropattern => Fluorescent Microscopy (FM), Atomic Force Microscopy (AFM), cell culture (mice osteoblasts)

    Responsibilities :

    -2018 : coordination of the LIESSE 2018 training “Physics, chemistry and mathematics in cell biology”, EMSE-CIS, Saint-Etienne
    -2018-2020 : Assistance and training to Atomic Force Microscopy (AFM) technique and use, EMSE-CIS, Saint-Etienne
    -2016-2017 : entrepreneurial support for a project aiming to democratize AFM technology with an educationnal approach

  • Skills

    Interdisciplinarity : Mechanical engineering/Cell biology
    Cell culture/Primary culture
    Applied physics & Instrumentation
    Atomic force Microscopy (AFM) (air and liquid)
    Fluorescent Microscopy (FM)
    Traction Force Microscopy (TFM)

  • Research Topics

    -2017/2020 : PhD Student/Research Engineer (SAINBIOSE INSERM U1059) => Investigation at the cellular/subcellular scale of the SMC’s biomechanical role in Ascending Thoracic Aortic Aneurysm (ATAA) theme (grant ERC-2014-CoG BIOLOCHANICS)

    -2017 : Dual degree : Engineering + Research Master in Biomechanics =>
    End-of-studies project on AFM+FM combination for the characterization of animal single cells fixed on adhesive micropattern : preparing further cross-disciplinary practical works for master students (CIME Nanotech, Grenoble).

    -2016-2018 : collaboration with an university lecturer and researcher, designing a new AFM equipment aiming to educational applications + entrepreneurial support for this project (corresponding training : D2E, BEELYS, Lyon, France)

  • Teaching Areas

    -LIESSE 2018 training : Lecture for preparatory class teachers : “Cell mechanics using Atomic Force Microscopy (AFM)”
    -2018 : Substitute teacher for the Institute of Technology of Saint-Etienne, Applied physics (MPh) department
    -2017 : Participation in the Nano@school program (CIME Nanotech, Grenoble) for the spreading of nanoscience and nanotechnology towards young public (secondary/high school)
    -2016-2018 : Regular presentations for the democratization of AFM technique towards general public

  • Education

    -2017-2020 : PhD thesis, Biomechanics, École des Mines de Saint-Étienne, France
    -2014-2017 : Engineering degree, Mechanical engineering + Sensory engineering, ENISE, Saint-Etienne, France
    -2015-2016 : Diplôme Etudiant-Entrepreneur (D2E) : entrepreneurship training, BEELYS, Lyon, France
    -2012-2014 : DUT graduate, Applied physics & Instrumentation (MPh department), Institute of Technology of Saint-Etienne, France

  • Main Publications

    Publications :

    -I. A. Ivan, C. Petit, I. V. Gurgu, R. Toscano,
    AFM Nanœye – Development of an education oriented high resolution profilometer, IFAC-PapersOnLine, Volume 50, Issue 1, 2017, p. 2385-2390,
    ISSN 2405-8963,