Research

Centre for Biomedical and Healthcare Engineering

“Improving health through Science and Engineering”

Head

Stéphane Avril
stephane.avril@mines-stetienne.fr

Research Fields

  • Mechanics
  • Material science
  • Physico-chemistry
  • Mathematics
  • Computer science
  • Image processing and biology

Human Resources

60 persons

  • 25 permanent faculty and staff
  • 35 Docs and Post-Docs

Industrial sectors

  • Biomedical devices, augmented medicine
  • Pharmacy, healthcare systems
  • Sports industry, cosmetics

Research units

  • SaInBioSE (INSERM U1059)
  • LIMOS (CNRS UMR 6158)

Scientific Departments

STBio – Soft Tissue BIOmechanics

Contact: Pierre Badel, pierre.badel@mines-stetienne.fr

  • Prevention of aneurysm ruptures
  • Biomechanical action of medical textiles
  • Numerical simulations
  • Biotribocorrosion of implants

I4S – Healthcare Engineering

Contact: Xiaolan Xie, xiaolan.xie@mines-stetienne.fr

  • Modelling,
  • Simulation and optimization of healthcare systems
  • Planning
  • Hospital logistics
  • Operational research

BioPI – BIOmaterial and inhaled nanoParticles

Contact: Jérémie Pourchez, jeremie.pourchez@mines-stetienne.fr

  • Synthesis and manufacturing of bioceramics
  • 3D printing
  • Aerosol metrology
  • Cell culture
  • Biotoxicity
  • Bio-physico-chemical characterization of materials

Platforms

Biomechanical

Contact: Baptiste Pierrat, baptiste.pierrat@mines-stetienne.fr

Poster (PDF)

Expertise
  • Mechanical characterization of soft tissues and textiles
    • Constitutive data characterization (Elastic modulus, Visco-elasticity, Anisotropy, Damage, …)
    • Fatigue testing
      Experience with biological tissues: arterial wall, linea alba, tendons, ligaments, skin, …
  • Evaluation of medical devices and sport equipment
    • 3D full field measurements: shapes, displacement and strain maps
    • Interface pressure measurements
    • In-silico evaluation of body/device mechanical interactions
  • Numerical simulation
    • Model generation from medical images
    • Non-linear finite element analysis
    • Solid mechanics, CFD
    • Parametric analyses
    • Constitutive model development and implementation
Equipment
  • Mechanical testing
    Electroforce biaxial test bench, Instron uniaxial tensile testing machine, FSA pressure mapping system…
  • Optical systems
    Stereo-correlation bench (with inflation test), fringe projection system, OCT, microscopes…
  • ​Softwares
    Finite element (Abaqus, Ansys, FEBio), Image processing (Simpleware, ImageJ), Numerical computing (Matlab), System-design (Labview, Arduino)
  • Computer cluster for parallel computing
​Applications
  • Cardiovascular biomechanics
    Patient-specific computer simulations for planning endovascular repairs
    Characterization of the rupture mechanisms of abdominal aortic aneurysms…
  • Musculoskeletal biomechanics
    Investigation of pressure applied by lumbar belts
    Evaluation of the mechanical effect of knee braces

Discrete Event and Numerical Simulation for Healthcare Decision Aid

Contact: Raksmey Phan, raksmey.phan@mines-stetienne.fr

  • Discrete event simulation of care pathways
  • Healthcare resource planning
  • Healthcare process design
  • Healthcare data analytics
  • Cluster computers (or High-Performance Computing) and application server

Biomaterials and aerosols platform

Contact: Lara Leclerc, lara.leclerc@mines-stetienne.fr

  • Synthesis (semi-industrial production), advanced shaping (tailor-made) and characterization of calcium phosphates bioceramics for bone tissue engineering.
    Applications: Development of calcium phosphates biomaterials and innovative (manufacturing) process, fabrication of functional prototypes and supporting companies in innovation and project set-up at industrial scale.
    Poster (PDF)
  • Aerosol generation and characterization – Deposition studies on anatomical models.
    Applications: Medical devices for aerosoltherapy, bioaerosols and e-cigarette for smoking cessation.
    Poster (PDF)
  • Nanoparticles detection and physico-chemical characterization in biological samples – In vitro biological activity evaluation – Air-liquid interface exposure (Vitrocell).
    Applications: Industrial nanotoxicology, mineralopathology.
    Poster (PDF)